20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40042 | Evifacotrep | TRP/TRPV Channel | |
Evifacotrep is a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100). Evifacotrep can be used for the research of neurological diseases. | |||
T7177 | Capsazepine | Apoptosis , TRP/TRPV Channel | |
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is ... | |||
T2298 | ML204 | TRP/TRPV Channel | |
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. | |||
T22124 | Oleoyl Serotonin | TRP/TRPV Channel | |
Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM. | |||
T12514 | Podocarpic acid | Others , TRP/TRPV Channel | |
Podocarpic acid is a natural product and a novel TRPA1 activator. | |||
T6848 | GSK1016790A | GSK101 | Calcium Channel , TRP/TRPV Channel |
GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells. | |||
T6977 | SB-366791 | SB366791 | TRP/TRPV Channel |
SB-366791 is a new and selective cinnamide TRPV1 antagonist. | |||
T6S1684 | 8-Gingerol | Antioxidant , Antibacterial , TRP/TRPV Channel | |
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic... | |||
T6617 | Optovin | TRP/TRPV Channel | |
Optovin is a TRPA1 activator, which is reversibly photoactivated. | |||
T1814 | ICILIN | AG-3-5 | TRP/TRPV Channel |
ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist. | |||
T2807 | Caffeic Acid | Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel | |
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities. | |||
T10537 | BI-749327 | TRP/TRPV Channel | |
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6). | |||
T5698 | TRPM8 antagonist 2 | TRP/TRPV Channel | |
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes. | |||
T6660 | SB-705498 | TRP/TRPV Channel | |
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis. | |||
T7430 | AM-0902 | TRP/TRPV Channel | |
AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1). | |||
T16763 | RN-1747 | TRP/TRPV Channel | |
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 μM, 4.0 μM, and 4.1 μM for hTRPV4, mTRPV4, and rTRPV4 respectively). RN-1747 also antagonizes TRPM8 (IC50: 4 μM... | |||
T15628 | JT010 | TRP/TRPV Channel | |
JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM). | |||
T9709 | TRPM8 antagonist 3 | TRP/TRPV Channel | |
TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM). | |||
T10300 | AMG2850 | TRP/TRPV Channel | |
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8). | |||
T5640 | GSK2193874 | TRP/TRPV Channel | |
GSK2193874 was identified as a selective, orally active TRPV4 blocker. |